It is clinically characterized by cognitive deterioration, a variety of neuropsychiatric symptoms, and restrictions in day-to-day activities.

Attention, psychomotor speed, memory, orientation, and executive functions, like thought, judgment, and behavior, can be disrupted; anxiety, delirium, hallucinations, agitation, irritability, and  / or speech disorders may appear.

Alzheimer´s disease is characterized by beta-amyloid protein deposition outside the neurons and abnormal fibers of the tau protein accumulated in the neurons.

According to the World Alzheimer Report of 2016, there are 47 million people with dementia worldwide, caused mainly by Alzheimer’s, and representing between 60 and 80 % of all the cases.

In general, Alzheimer’s disease does not show disorders in the form of micro infarctions, which are seen in senile dementia of vascular origin, where multiple micro infarctions start causing neuronal loss and producing similar symptoms to Alzheimer’s.

Both diseases can also coexist in one patient.

The event-related neurophysiological studies may have a significant contribution in the differentiation between these two diseases that generate senile dementia to select the most adequate care.